Queen's University
Characterizing the Replication Rate and Error  Rate of DNA Polymerase I in Microgravity — PI: Dr. Virginia Katrina Walker. Space  radiation has damaging effects on human DNA , a molecule essential for biological function, acting as the genetic  code for all life. This challenge has been well  documented, but the effectiveness of DNA repair and replication pathways in a  zero-gravity environment has yet to be investigated. As we prepare for long-duration missions, there is a need to address this  problematic. This  project aims to investigate the function of the DNA polymerase I, an enzyme  involved in the repair and replication of DNA , in conditions of microgravity.  This experiment will help increase understanding of the issues related to  maintaining the integrity of astronauts' DNA in space.