Mount Saint Vincent University
Deciphering simulated microgravity and vibration effects on bone tissue in vivo — Following a space mission, astronauts experience severe bone thinning and increased risks of fracture when back on Earth. This bone anomaly is due to the exposure to an environment with reduced gravitational forces, namely microgravity. The aim of this study is to reproduce the microgravity environment on Earth using a ground-based instrument. Researchers will expose fish larvae to a simulated microgravity environment and analyse the effects on bone cells in the skeleton. The counter measure of vibration will also be examined separately and in combination with microgravity. The objectives of the study are to understand the cellular responses to these treatments in order to understand the microgravity induced bone loss observed in astronauts and to understand how to reduce these effects with vibration exposures. Fish bones strongly resemble human bones, in that the same cells are present, therefore these results will be relevant to humans.