Ottawa University
The RNA-binding protein Staufen1 as a novel therapeutic target for skeletal muscle atrophy — Skeletal muscle atrophy is a health concern for human on Earth and for astronauts involved in space flight due to decrease in muscle size and strength which increases fatigability and frailty. The success of long-term space flight is partly limited by the health concerns and risks to the astronauts involved in these missions. The focus of this project is to: i) better understand how muscle atrophy occurs; and ii) eventually design novel therapeutic interventions to counteract the devastating impact of atrophy on Earth and in space.